Bacterial infections, immune overload, and MMR vaccine. Measles, mumps, and rubella

E Miller; N Andrews; P Waight; B Taylor

doi:10.1136/adc.88.3.222

Bacterial infections, immune overload, and MMR vaccine. Measles, mumps, and rubella

Arch Dis Child. 2003 Mar;88(3):222-3. doi: 10.1136/adc.88.3.222.

Authors

E Miller¹, N Andrews, P Waight, B Taylor

Affiliation

¹ Immunisation Division, Communicable Disease Surveillance Centre, Public Health Laboratory Service, 61 Colindale Avenue, London NW9 5EQ, UK. [email protected]

Abstract

Combined measles, mumps, and rubella (MMR) vaccine did not increase the risk of hospitalisation with invasive bacterial infection in the three months after vaccination; rather there was a protective effect. These results provide no support for the concept of "immunological overload" induced by multiple antigen vaccinations, nor calls for single antigen vaccines.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Bacterial Infections / immunology*
Bacterial Infections / prevention & control
Child, Preschool
Female
Hospitalization
Humans
Male
Measles-Mumps-Rubella Vaccine / adverse effects
Measles-Mumps-Rubella Vaccine / immunology*
Pneumonia, Pneumococcal / immunology
Risk Factors

Substances

Measles-Mumps-Rubella Vaccine