Objective of this study was to detect regional myocardial perfusion defects performing (99m)Tc-MIBI myocardial perfusion imaging and to compare the results with echocardiography for differential diagnostics of the ischemic and hypertensive cardiomyopathy until coronary angiography will be performed.
Material and methods: In total 50 patients with cardiomegaly have been evaluated: 18 patients with hypertensive cardiomyopathy (I(st) group), 15 - with ischemic and hypertensive cardiomyopathy (II(nd) group) and 17 patients with ischemic cardiomyopathy (III(rd) group). All patients underwent 2D echocardiography examination and (99m)Tc-MIBI myocardial perfusion imaging before coronary angiography was done.
Results: Thickness of interventricular septum, myocardial mass and relative wall thickness were statistically significantly smaller in the III(rd) group of patients in comparison with the I(st) and the II(nd) group of patients.
Conclusions: Logistic regression model including selected data from myocardial perfusion imaging with (99m)Tc-MIBI in combination with selected echocardiography data enables prognosis of coronary arteries stenosis with 91.2% sensitivity and 93.8% specificity.