Interferon-gamma reduces interleukin-4- and interleukin-13-augmented transforming growth factor-beta2 production in human bronchial epithelial cells by targeting Smads

Chest. 2003 Mar;123(3 Suppl):372S-3S.

Authors

Fu-Qiang Wen¹, Xiangde D Liu, Yusuke Terasaki, Qiuhong H Fang, Tetsu Kobayashi, Shinji Abe, Stephen I Rennard

Affiliation

¹ Pulmonary and Critical Care Medicine Section, University of Nebraska Medical Center, Omaha, NE 68198-5125, USA.

PMID: 12628985

No abstract available

Publication types

Review

MeSH terms

Adjuvants, Immunologic / pharmacology*
Antiviral Agents / pharmacology*
Bronchi / drug effects*
Bronchi / metabolism*
DNA-Binding Proteins / drug effects*
Epithelial Cells / drug effects*
Epithelial Cells / metabolism*
Humans
Immunosuppressive Agents / analysis*
In Vitro Techniques
Interferon-gamma / pharmacology*
Interleukin-13 / pharmacology*
Interleukin-4 / pharmacology*
Signal Transduction / drug effects
Smad Proteins
Trans-Activators / drug effects*
Transforming Growth Factor beta / analysis*
Transforming Growth Factor beta2

Substances

Adjuvants, Immunologic
Antiviral Agents
DNA-Binding Proteins
Immunosuppressive Agents
Interleukin-13
Smad Proteins
TGFB2 protein, human
Trans-Activators
Transforming Growth Factor beta
Transforming Growth Factor beta2
Interleukin-4
Interferon-gamma