Comparison of lactate, bilirubin and hemoglobin F concentrations obtained by the ABL 700 series blood gas analyzers with laboratory methods

Clin Biochem. 2003 Mar;36(2):103-7. doi: 10.1016/s0009-9120(02)00449-6.

Abstract

Objective: To compare lactate, bilirubin and Hemoglobin F concentrations obtained on ABL 700 series blood gas analyzers with those from laboratory methods.

Design and method: Pooled neonatal plasma, cord blood and adult plasma samples were used for comparison of bilirubin, hemoglobin F and lactate concentrations respectively.

Results: Results obtained on the ABL 700 series compared favorably (Deming regression slopes 0.97-1.13) with those from laboratory methods. For lactate ABL (y) = 1.13 Vitros (x) -0.43 with a CI (slope) of 1.10 to 1.16, CI (int) of -0.61 to -0.28. For hemoglobin F ABL(y) = 1.11 Variant (x) -8.0 with a CI (slope) of 0.88 to 1.33, CI (int) of -25.3 to 9.3. The three bilirubin comparisons are as follows: 1) Unistat (y) = 1.10 Vitros (x) -16.12 with CI (slope) of 1.06 to 1.14 and CI (int) of -25.3 to -6.9. 2), ABL (y) = 0.97 Vitros(x) -10.16 with CI (slope) of 0.94 to 1.00 and CI (int) of -17.6 to 2.73) Unistat (y) = 1.14 (x)-4.58 with CI (slope) of 1.09 to 1.18 and CI (int) of -13.6 to 4.5.

Conclusion: The ABL 700 series gave comparable results for lactate, bilirubin and hemoglobin F with laboratory methods and may be used in patient care.

Publication types

  • Comparative Study

MeSH terms

  • Adult
  • Bilirubin / blood*
  • Blood Gas Analysis / instrumentation
  • Blood Gas Analysis / methods*
  • Blood Gas Analysis / standards
  • Fetal Blood / chemistry
  • Fetal Hemoglobin / analysis*
  • Humans
  • Infant, Newborn
  • Lactates / blood*
  • Linear Models
  • Reference Standards
  • Regression Analysis
  • Reproducibility of Results

Substances

  • Lactates
  • Fetal Hemoglobin
  • Bilirubin