Terpene biosynthesis in the nudibranch Doriopsilla areolata

J Org Chem. 2003 Mar 21;68(6):2405-9. doi: 10.1021/jo026131v.

Abstract

Biogenesis of the enantiomeric sesquiterpenes 1 and 5 of the marine nudibranch Doriopsilla areolata was investigated by feeding of [1-(13)C]glucose, [1,2-(13)C(2)]glucose, and [1,2-(13)C(2)]acetate. Evidence is presented that supports de novo origin of both compounds via mevalonic acid.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Acetates / metabolism*
  • Animals
  • Carbon Isotopes
  • Catalysis
  • Glucose / metabolism*
  • Mevalonic Acid / metabolism
  • Molecular Structure
  • Mollusca / chemistry*
  • Nuclear Magnetic Resonance, Biomolecular
  • Sesquiterpenes / metabolism*
  • Stereoisomerism
  • Terpenes*

Substances

  • Acetates
  • Carbon Isotopes
  • Sesquiterpenes
  • Terpenes
  • Glucose
  • Mevalonic Acid