Purely follicular mycosis fungoides without mucinosis: report of two cases with review of the literature

J Am Acad Dermatol. 2003 Mar;48(3):448-52. doi: 10.1067/mjd.2003.140.

Abstract

Follicular lesions can either associate with typical patch-/plaque-type mycosis fungoides or, more rarely, be the only clinical manifestation of the disease. We describe 2 adult patients who presented with alopecia and disseminated follicular erythematous papules, and comedones and cysts, respectively. In both patients, histology showed a folliculotropic infiltrate of atypical lymphocytes that spared the epidermis, in the absence of follicular mucinosis. Molecular genetic analysis confirmed the oligo/monoclonal nature of the T-cell infiltrate. Reported cases of purely follicular mycosis fungoides without mucinosis are reviewed.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Aged
  • Biopsy, Needle
  • Drug Therapy, Combination
  • Female
  • Humans
  • Immunohistochemistry
  • Male
  • Middle Aged
  • Mucinosis, Follicular / pathology*
  • Mycosis Fungoides / diagnosis
  • Mycosis Fungoides / drug therapy
  • Mycosis Fungoides / pathology*
  • Prognosis
  • Risk Assessment
  • Skin Neoplasms / diagnosis
  • Skin Neoplasms / drug therapy
  • Skin Neoplasms / pathology*