An improved methodology for the synthesis of enantiomerically pure (S)-2,3-O-cyclohexylideneglyceraldehyde

Enantiomer. 2002 Nov-Dec;7(6):383-5. doi: 10.1080/10242430215702.

Abstract

An improved methodology to prepare (S)2,3-O-cyclohexylideneglyceraldehyde is described. Starting from the commercially available (L)-cyclohexylidene protected ascorbic acid the enantiomerically pure aldehyde was synthesized in only two steps in 41% overall yield.