Sarcoidosis after use of interferon for chronic hepatitis C: report of a case and review of the literature

V Tahan; F Ozseker; D Guneylioglu; A Baran; R Ozaras; A Mert; A C Ucisik; T Cagatay; D Yilmazbayhan; H Senturk

doi:10.1023/a:1021759120428

Sarcoidosis after use of interferon for chronic hepatitis C: report of a case and review of the literature

Dig Dis Sci. 2003 Jan;48(1):169-73. doi: 10.1023/a:1021759120428.

Authors

V Tahan¹, F Ozseker, D Guneylioglu, A Baran, R Ozaras, A Mert, A C Ucisik, T Cagatay, D Yilmazbayhan, H Senturk

Affiliation

¹ Gastroenterology Institute, Marmara University, Istanbul, Turkey.

PMID: 12645805
DOI: 10.1023/a:1021759120428

Abstract

Although interferon has not been classified in the pathogenesis of sarcoidosis, it may rarely lead to this disease during treatment of chronic hepatitis C. The case of a 36-year-old woman with chronic hepatitis C who developed sarcoidosis within 10 weeks of treatment with recombinant interferon-alpha2a and ribavirin is described and all seven similar cases published in English from 1989 to 2001 are discussed.

Publication types

Case Reports
Review

MeSH terms

Adult
Antiviral Agents / adverse effects*
Antiviral Agents / therapeutic use
Drug Therapy, Combination
Female
Hepatitis C, Chronic / drug therapy*
Humans
Interferon alpha-2
Interferon-alpha / adverse effects*
Interferon-alpha / therapeutic use
Recombinant Proteins
Ribavirin / adverse effects
Ribavirin / therapeutic use
Sarcoidosis, Pulmonary / chemically induced*

Substances

Antiviral Agents
Interferon alpha-2
Interferon-alpha
Recombinant Proteins
Ribavirin