Cytochrome c(551) as a model system for protein folding

Biophys Chem. 2003;100(1-3):409-19. doi: 10.1016/s0301-4622(02)00295-8.

Abstract

Considerable progress was made over the last few years in understanding the mechanism of folding of cytochrome c(551), a small acidic hemeprotein from Pseudomonas aeruginosa. Comparison of our results with those obtained by others on horse heart cytochrome c allows to draw some general conclusions on the structural features that are common determinants in the folding of members of the cytochrome c family.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Bacterial Proteins / chemistry*
  • Bacterial Proteins / genetics
  • Cytochrome c Group / chemistry*
  • Cytochrome c Group / genetics
  • Guanidine / chemistry
  • Kinetics
  • Models, Chemical
  • Mutation / genetics
  • Protein Conformation
  • Protein Denaturation
  • Protein Folding*
  • Pseudomonas aeruginosa / enzymology
  • Urea / chemistry

Substances

  • Bacterial Proteins
  • Cytochrome c Group
  • Urea
  • cytochrome C(551)
  • Guanidine