Minimal handling and bronchopulmonary dysplasia in extremely low-birth-weight infants

Eur J Pediatr. 2003 Apr;162(4):227-9. doi: 10.1007/s00431-002-1131-5. Epub 2003 Feb 7.

Abstract

Over the last 16 years a minitouch regime, i.e., nasal continuous positive airway pressure (n-CPAP) and/or nasal intermittent positive pressure ventilation (n-IPPV), together with a minimal intubation policy has been routinely used for the treatment of respiratory distress syndrome (RDS) in preterm infants. Only 1.39 (1 out of 72) of the extremely low-birth-weight babies admitted to our Neonatal Intensive Care Unit (NICU) and surviving for at least 36 weeks' postconceptional age developed bronchopulmonary dysplasia at 36 weeks (BPD 36-wk). The BPD-36 wk incidence observed in our population is significantly lower than expected (30%) from the literature (p=0.000002).

Conclusion: Our experience supports the effectiveness of the minitouch regime as a way to ventilate premature babies, reducing BPD risk.

MeSH terms

  • Birth Weight
  • Bronchopulmonary Dysplasia / prevention & control*
  • Female
  • Gestational Age
  • Humans
  • Infant, Newborn
  • Infant, Very Low Birth Weight*
  • Intermittent Positive-Pressure Ventilation*
  • Intubation, Intratracheal / methods*
  • Male
  • Oxygen / administration & dosage
  • Positive-Pressure Respiration*
  • Respiratory Distress Syndrome, Newborn / therapy*
  • Risk Factors
  • Survival Analysis

Substances

  • Oxygen