Compliance with a protocol for intrapartum antibiotic prophylaxis against neonatal group B streptococcal sepsis in women with clinical risk factors

Infect Dis Obstet Gynecol. 2002;10(4):223-9. doi: 10.1155/S1064744902000261.

Abstract

Objective: The aim of this study was to determine the prevalence of clinical risk factors (CRF) for neonatal sepsis in laboring women and to evaluate clinician compliance with a CRF-based protocol for intrapartum antibiotic prophylaxis (IAP).

Methods: A retrospective chart audit was undertaken at a district hospital (A) and a tertiary obstetric hospital (B) in Sydney, Australia between 1996 and 1998, to determine compliance with IAP in women with defined CRF.

Results: Eighty-five (12%) women at Hospital A and 117 (19%) at Hospital B had one or more CRF. Overall compliance rates with the IAP protocols were 65 and 50% at Hospitals A and B respectively, but varied according to maternal, obstetric and sepsis-related risk factors. We postulate that differences between the hospitals were related to protocol implementation.

Conclusions: Compliance with a CRF-based protocol was lower than previously reported. Improvements in protocol development, implementation and maintenance are required to enhance compliance with IAP based on CRF.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Antibiotic Prophylaxis / standards*
  • Delivery, Obstetric
  • Female
  • Gestational Age
  • Guideline Adherence / statistics & numerical data*
  • Hospitals, Community / standards
  • Hospitals, Maternity / standards
  • Humans
  • Infant, Newborn
  • Labor, Obstetric
  • Medical Records
  • New South Wales / epidemiology
  • Pregnancy
  • Pregnancy Complications, Infectious / epidemiology
  • Pregnancy Complications, Infectious / prevention & control*
  • Prevalence
  • Retrospective Studies
  • Risk Factors
  • Sepsis / epidemiology
  • Sepsis / prevention & control*
  • Streptococcal Infections / epidemiology
  • Streptococcal Infections / prevention & control*
  • Streptococcus agalactiae / isolation & purification