Abstract
Genotypic analysis of Mycobacterium tuberculosis isolates obtained from human immunodeficiency virus type 1 (HIV-1)-seropositive (n = 80) and -seronegative (n = 25) patients from Lima, Peru, revealed two distinct genotypes correlating with the host immune status. While the level of intrastrain diversity of DNA fingerprints of HIV-seropositive isolates was less pronounced, these isolates showed many clonal groupings.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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AIDS-Related Opportunistic Infections / microbiology
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DNA Fingerprinting / methods
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Genotype
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HIV Seronegativity*
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HIV Seropositivity / complications*
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Humans
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Mycobacterium tuberculosis / classification*
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Mycobacterium tuberculosis / genetics*
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Mycobacterium tuberculosis / isolation & purification
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Peru
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Phylogeny
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Polymorphism, Restriction Fragment Length
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Tuberculosis, Pulmonary / complications
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Tuberculosis, Pulmonary / microbiology*