A rare case of a pulmonary granular cell tumor presenting as a coin lesion

Jpn J Thorac Cardiovasc Surg. 2003 Mar;51(3):107-9. doi: 10.1007/s11748-003-0082-8.

Abstract

A 38-year-old man was found to show a well-defined oval-shaped homogeneous dense mass (20 x 30 mm) in the left upper lung field on chest X-ray. Left upper divisionectomy was performed under video-assisted thoracic surgery. Histology showed that the tumor cells had abundant eosinophilic granular cytoplasm, and were immunopositive for neuron-specific enolase, CD56, S-100 protein, and chromogranin. The proportion of Ki-67 positive cells was < 1%. An electron-microscopic examination showed many membrane-bound whorls in the cytoplasm. Although this was a very rare case presenting as an asymptomatic coin lesion, the histological features were the same as those demonstrated for granular cell tumor at common sites.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Diagnosis, Differential
  • Granular Cell Tumor / diagnosis*
  • Granular Cell Tumor / pathology
  • Humans
  • Lung Neoplasms / diagnosis*
  • Lung Neoplasms / pathology
  • Male
  • Solitary Pulmonary Nodule / diagnosis*
  • Solitary Pulmonary Nodule / pathology