Abstract
We encountered a case of small-cell lung cancer with paraneoplastic neurologic syndrome in a 68-year old man. Progressive dysesthesia had developed in his hands and legs over a period of 4 months. Chest radiography and chest CT scanning on admission showed a mass in the hilum of the left lung. Anti-Hu antibody was found in his serum and the subsequent histopathological diagnosis by TBLB was small cell lung cancer. The patient underwent complete remission, in terms of tumor size, as a result of concurrent chemoradiotherapy (cisplatin, etoposid) and the dysesthesia in his legs was alleviated.
Publication types
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Case Reports
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English Abstract
MeSH terms
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Aged
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Autoantibodies / blood*
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Biomarkers, Tumor / blood*
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Carcinoma, Small Cell / complications*
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Carcinoma, Small Cell / diagnosis*
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Carcinoma, Small Cell / therapy
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Combined Modality Therapy
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ELAV Proteins
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Humans
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Lung Neoplasms / complications*
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Lung Neoplasms / diagnosis*
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Lung Neoplasms / therapy
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Male
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Paraneoplastic Polyneuropathy / diagnosis*
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Paraneoplastic Polyneuropathy / etiology*
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Paraneoplastic Polyneuropathy / therapy
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Paresthesia / etiology
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Paresthesia / therapy
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RNA-Binding Proteins / immunology*
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Treatment Outcome
Substances
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Autoantibodies
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Biomarkers, Tumor
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ELAV Proteins
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RNA-Binding Proteins