Purpose: To report the occurrence of two entirely separate choroidal melanomas in the same eye of one patient.
Design: Observational case report.
Methods: Retrospective case report from one clinical practice. Two choroidal melanomas were observed to develop in the same eye of one patient.
Results: An inferonasal choroidal melanoma was diagnosed in the left eye of a 30-year-old woman in 1990. This was successfully treated with proton beam radiotherapy. In 1996, a superotemporal choroidal tumor in the same eye was observed to grow rapidly and it was treated with a ruthenium plaque in 1996. There was a history of cutaneous malignant melanoma.
Conclusions: It is extremely rare for two choroidal melanomas to develop in one eye, and there may be a genetic predisposition.