Contrast-enhanced peripheral MR angiography at 3.0 Tesla: initial experience with a whole-body scanner in healthy volunteers

J Magn Reson Imaging. 2003 May;17(5):609-14. doi: 10.1002/jmri.10297.

Abstract

Purpose: To report preliminary experience with contrast-enhanced magnetic resonance angiography (CE-MRA) of the peripheral arteries on a 3.0 T whole-body scanner equipped with a prototype body coil.

Materials and methods: Four healthy volunteers were imaged on the 3.0 T system and, for comparative purposes, two of the subjects were also imaged on a commercially available 1.5 T whole-body system. To investigate field strength influence on objective image quality, signal-to-noise (SN) and contrast-to-noise (CN) ratios were calculated for named vessels from the infrarenal aorta to the ankles at both field strengths. Comparable imaging protocols were used at both field strengths. In addition, two reviewers, blinded for field strength, gave subjective image quality scores (three-point scale).

Results: SN and CN ratios were approximately equal on both systems (variation < or =9%) for the iliac and proximal upper leg stations. For the popliteal and lower leg stations SN ratios were 36% and 97% higher, and CN ratios were 44% and 127% higher, at 3.0 T. Subjective image quality at 3.0 T was substantially better for the distal upper and lower legs.

Conclusion: Contrast-enhanced peripheral MRA is possible at 3.0 T when an imaging protocol similar to a current state-of-the-art 1.5 T protocol is used. Objective and subjective image quality at 3.0 T is comparable for the iliac and upper legs but better for the popliteal and lower leg arteries.

Publication types

  • Evaluation Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Arterial Occlusive Diseases / diagnosis*
  • Contrast Media*
  • Feasibility Studies
  • Female
  • Gadolinium DTPA*
  • Humans
  • Iliac Artery / anatomy & histology
  • Magnetic Resonance Angiography / methods*
  • Male
  • Popliteal Artery / anatomy & histology

Substances

  • Contrast Media
  • Gadolinium DTPA