Invasive aspergillosis in solid-organ transplantation: report of eight cases and review of the literature

Transpl Int. 2003 Apr;16(4):280-6. doi: 10.1007/s00147-002-0522-x. Epub 2003 Feb 13.

Abstract

Invasive fungal infections are life-threatening complications in solid-organ transplantation. Although the rate of fungal infections in transplant recipients is lower than that of other infections, the mortality rate is higher. The most frequent fungi isolated from these kinds of infections are Candida spp. and Aspergillus spp. We retrospectively evaluated the clinical and laboratory findings in eight patients who were treated for invasive aspergillosis (IA) at our center. This report describes these cases and discusses the relevant literature.

MeSH terms

  • Adult
  • Antifungal Agents / therapeutic use*
  • Aspergillosis / drug therapy
  • Aspergillosis / etiology*
  • Humans
  • Immunosuppressive Agents / adverse effects
  • Kidney Transplantation / adverse effects*
  • Liver Transplantation / adverse effects*
  • Middle Aged
  • Retrospective Studies

Substances

  • Antifungal Agents
  • Immunosuppressive Agents