Motion of an adhesive gel in a swelling gradient: a mechanism for cell locomotion

Phys Rev Lett. 2003 Apr 25;90(16):168102. doi: 10.1103/PhysRevLett.90.168102. Epub 2003 Apr 25.

Abstract

Motivated by the motion of nematode sperm cells, we present a model for the motion of an adhesive gel on a solid substrate. The gel polymerizes at the leading edge and depolymerizes at the rear. The motion results from a competition between a self-generated swelling gradient and the adhesion on the substrate. The resulting stress provokes the rupture of the adhesion points and allows for the motion. The model predicts an unusual force-velocity relation which depends in significant ways on the point of application of the force.

MeSH terms

  • Adhesives / chemistry*
  • Animals
  • Ascaris
  • Cell Movement / physiology*
  • Elasticity
  • Gels / chemistry*
  • Male
  • Models, Chemical*
  • Spermatozoa / physiology

Substances

  • Adhesives
  • Gels