Abstract
One hundred ninety-three Streptococcus agalactiae isolates of neonatal origin and 146 isolates from adult women were analyzed for macrolide resistance and investigated for clonality. Among erythromycin-resistant isolates, serotype V turned out to be the most frequent. Comparative pulsed-field gel electrophoresis analysis revealed genetic clustering of resistant strains and predominance of a single clone family within an otherwise heterogeneous serotype V population.
MeSH terms
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Adult
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Anti-Bacterial Agents / pharmacology*
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DNA, Bacterial / genetics
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DNA, Bacterial / isolation & purification
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Drug Resistance, Bacterial / genetics
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Electrophoresis, Gel, Pulsed-Field
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Erythromycin / pharmacology*
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Female
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Genes, Bacterial
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Humans
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Infant, Newborn
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Pregnancy
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Serotyping
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Streptococcal Infections / drug therapy
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Streptococcal Infections / microbiology
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Streptococcus agalactiae / classification*
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Streptococcus agalactiae / drug effects*
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Streptococcus agalactiae / genetics
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Streptococcus agalactiae / isolation & purification
Substances
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Anti-Bacterial Agents
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DNA, Bacterial
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Erythromycin