Behçet's disease is a chronic systemic vasculitis with unknown etiology characterized by recurrent oral and genital ulcerations, ocular inflammation,having manifestations related to the skin and joints. Neurologic, pulmonary and gastrointestinal findings can also be observed during the course of the disease. In this report a case of Behçet's disease that had amyloidosis due to renal parenchymal involvement of the disease showing itself by nephrotic syndrome is presented.