Post-extrasystolic potentiation recruits incremental contractile reserve of dyssynergic myocardium during dobutamine stress testing: evidence by pulsed wave tissue Doppler imaging

Eur J Echocardiogr. 2003 Jun;4(2):148-51. doi: 10.1053/euje.2002.0618.

Abstract

Dobutamine stress echocardiography is an established diagnostic method for the detection of myocardial viability in patients with severe left ventricular dysfunction([1]). The presence of viable myocardium identifies patients who will benefit from coronary revascularization, by improving both functional capacity and long-term survival. Occasionally, dobutamine infusion has been combined with other stressors, such as post-extrasystolic potentiation, in order to improve accuracy. The contractile reserve after combined dobutamine infusion and post-extrasystolic potentiation can be quantified by pulsed wave tissue Doppler imaging. We describe a patient with severe left ventricular dysfunction, in which pulsed wave tissue Doppler imaging allowed to demonstrate that post-extrasystolic potentiation superimposed on dobutamine infusion is able to further recruit contractile reserve, as compared to dobutamine infusion alone. A nuclear scan assessing glucose utilization was used as a reference.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Cardiac Complexes, Premature / diagnosis*
  • Cardiac Complexes, Premature / physiopathology*
  • Echocardiography, Doppler, Pulsed
  • Echocardiography, Stress*
  • Fluorodeoxyglucose F18
  • Humans
  • Male
  • Myocardial Contraction / physiology*
  • Myocardium / pathology*
  • Radiopharmaceuticals
  • Tomography, Emission-Computed, Single-Photon
  • Ventricular Dysfunction, Left / diagnosis
  • Ventricular Dysfunction, Left / physiopathology

Substances

  • Radiopharmaceuticals
  • Fluorodeoxyglucose F18