Airborne allergic contact dermatitis from 3-iodo-2-propynyl-butylcarbamate at a paint factory

Contact Dermatitis. 2003 Mar;48(3):155-7. doi: 10.1034/j.1600-0536.2003.00079.x.

Abstract

3-Iodo-2-propynyl-butylcarbamate (IPBC) is a fungicide used in both industrial products and cosmetics. We report the first case of allergic contact dermatitis from airborne exposure to this preservative. A 34-year-old female production worker at a paint factory developed dermatitis on air-exposed skin areas. Patch testing showed a ++ reaction to the preservative IPBC 0.01% in petrolatum. The compound was used as a preservative in wood treatment products manufactured at her work place. Based on animal studies, IPBC is considered safe as a cosmetic preservative. However, widespread use of the chemical might lead to increasing levels of contact allergy, and therefore, close monitoring of IPBC is recommended.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Air Pollution, Indoor / adverse effects*
  • Allergens / adverse effects*
  • Carbamates / adverse effects*
  • Dermatitis, Allergic Contact / diagnosis*
  • Dermatitis, Allergic Contact / etiology
  • Dermatitis, Occupational / diagnosis*
  • Dermatitis, Occupational / etiology
  • Diagnosis, Differential
  • Female
  • Humans
  • Paint / adverse effects
  • Patch Tests
  • Preservatives, Pharmaceutical / adverse effects*

Substances

  • Allergens
  • Carbamates
  • Preservatives, Pharmaceutical
  • 3-iodo-2-propynylbutylcarbamate