Prospective trial of radiotherapy after hyperbaric oxygenation with chemotherapy for high-grade gliomas

Radiother Oncol. 2003 Apr;67(1):63-7. doi: 10.1016/s0167-8140(02)00406-1.

Abstract

Twenty-one patients with high-grade gliomas were enrolled in a prospective trial of radiotherapy after hyperbaric oxygenation (HBO). Radiotherapy was administered in daily 2-Gy fractions up to a total dose of 60 Gy, and each fraction was delivered immediately after HBO. The current study indicated that radiotherapy immediately after HBO with chemotherapy was feasible for high-grade gliomas.

MeSH terms

  • Adult
  • Aged
  • Antineoplastic Combined Chemotherapy Protocols / therapeutic use
  • Combined Modality Therapy
  • Female
  • Glioblastoma / drug therapy
  • Glioblastoma / radiotherapy
  • Glioblastoma / therapy
  • Glioma / drug therapy
  • Glioma / radiotherapy
  • Glioma / therapy*
  • Humans
  • Hyperbaric Oxygenation*
  • Japan
  • Male
  • Middle Aged
  • Nimustine / administration & dosage
  • Procarbazine / administration & dosage
  • Prospective Studies
  • Supratentorial Neoplasms / drug therapy
  • Supratentorial Neoplasms / radiotherapy
  • Supratentorial Neoplasms / therapy*
  • Survival Rate
  • Vincristine / administration & dosage

Substances

  • Nimustine
  • Procarbazine
  • Vincristine