Imaging-guided percutaneous radiofrequency ablation of solid renal masses: techniques and outcomes of 38 treatment sessions in 32 consecutive patients

AJR Am J Roentgenol. 2003 Jun;180(6):1503-8. doi: 10.2214/ajr.180.6.1801503.

Abstract

Objective: The purpose of this study was to describe the treatment techniques and results of 38 consecutive imaging-guided percutaneous radiofrequency ablations of solid renal masses performed in 32 patients.

Materials and methods: Solid renal masses in 32 patients underwent 38 treatment sessions using imaging-guided percutaneous radiofrequency ablation. During 36 sessions, radiofrequency ablation was performed using CT guidance, and two, using sonographic guidance. The average patient age was 76 years (range, 52-87 years), and the average renal mass size was 2.6 cm (range, 1-5 cm). The average number of radiofrequency treatments per solid mass at each session was 2.4 (range, 1-6 treatments), and the average time per treatment was 9.2 min (range, 3-14 min). A single electrode was used in 12 sessions, and a cluster electrode was used in 26 sessions. The average follow-up time was 9 months (range, 1-36 months).

Results: Twenty-six of 32 patients had successful treatment of the solid renal mass using percutaneous imaging-guided radiofrequency ablation after one treatment session. Successful treatment was defined as lack of enhancement of the treated region on follow-up CT. Six of 32 patients had residual enhancing tissue after the first treatment session and returned for a second session. Five of these six retreatments were successful. Masses requiring a second treatment session were significantly larger than masses treated in a single session (3.5 vs 2.4 cm, respectively; p = 0.0013). Two patients had perinephric hematomas (which did not require transfusion), and one patient developed a 5-mm skin metastasis at the electrode insertion site, which was resected without recurrence.

Conclusion: Percutaneous imaging-guided radiofrequency ablation shows promise in the treatment of solid renal malignancies.

MeSH terms

  • Adenoma, Oxyphilic / diagnostic imaging*
  • Adenoma, Oxyphilic / surgery*
  • Aged
  • Aged, 80 and over
  • Angiomyolipoma / diagnostic imaging*
  • Angiomyolipoma / surgery*
  • Carcinoma, Renal Cell / diagnostic imaging*
  • Carcinoma, Renal Cell / surgery*
  • Catheter Ablation*
  • Female
  • Follow-Up Studies
  • Humans
  • Kidney Neoplasms / diagnostic imaging*
  • Kidney Neoplasms / surgery*
  • Male
  • Middle Aged
  • Outcome Assessment, Health Care*
  • Retrospective Studies
  • Surgery, Computer-Assisted*
  • Time Factors
  • Tomography, X-Ray Computed
  • Ultrasonography