Evidence to support the existence of subgroups within the UK epidemic Clostridium difficile strain (PCR ribotype 1)

W N Fawley; J Freeman; M H Wilcox

doi:10.1016/s0195-6701(03)00079-3

Evidence to support the existence of subgroups within the UK epidemic Clostridium difficile strain (PCR ribotype 1)

J Hosp Infect. 2003 May;54(1):74-7. doi: 10.1016/s0195-6701(03)00079-3.

Authors

W N Fawley¹, J Freeman, M H Wilcox

Affiliation

¹ Department of Microbiology, The University of Leeds and Leeds General Infirmary, Old Medical School, Leeds LS2 9JT, UK.

PMID: 12767851
DOI: 10.1016/s0195-6701(03)00079-3

Abstract

We used three different DNA fingerprinting techniques and clindamycin susceptibility testing to confirm that Clostridium difficile PCR ribotype I isolates can be divided into two subclones. This observation may permit a better understanding of the epidemiology and pathogenicity of C. difficile infection.

MeSH terms

Clindamycin / pharmacology*
Clostridioides difficile / classification
Clostridioides difficile / drug effects*
Clostridioides difficile / genetics*
Clostridioides difficile / isolation & purification
Clostridioides difficile / pathogenicity
Clostridium Infections / epidemiology*
Clostridium Infections / etiology
Clostridium Infections / microbiology
Cross Infection / epidemiology
Cross Infection / etiology
Cross Infection / microbiology
DNA Fingerprinting
Disease Outbreaks*
England / epidemiology
Humans
Microbial Sensitivity Tests
Polymerase Chain Reaction
Ribotyping

Substances

Clindamycin