Objective: To study the chemical constituents of Ligularia vellerea.
Method: The compounds were isolated by column chromatography, and the structures were identified by NMR spectral data and other methods.
Result and conclusion: Seven compounds were isolated and identified as 4-hydroxyacetophenone, 8 alpha-hydroxy-7(11)-eremophilen-12, 8 beta-olide, umbelliferone, tiglic acid, 6 beta-hydroxy-7(11)-eremophilen-12, 8 alpha-olide, daucosterin, beta-sitosterol and stigmasterol. All the compounds were isolated for the first time from this plant.