Radiation safety issues with high activities of liquid I-125: techniques and experience

J Appl Clin Med Phys. 2003 Spring;4(2):143-8. doi: 10.1120/jacmp.v4i2.2529.

Abstract

The handling of a liquid radioactive source is a procedure that is uncommon for the average clinical medical physicist. A newly approved treatment device utilizes high activities of liquid I-125 solution as the source of radiation. The radiation safety issues and our experience utilizing high activity liquid I-125 sources are presented. To date we have treated 22 patients with infused activities ranging up to 26.8 GBq (724 mCi). The careful manipulation of such solutions is important to maintain a safe environment for the patients and the involved medical staff.

MeSH terms

  • Benzenesulfonates / chemistry
  • Benzenesulfonates / therapeutic use
  • Benzenesulfonates / urine
  • Brachytherapy / instrumentation*
  • Brachytherapy / methods
  • Brachytherapy / trends*
  • Brain Neoplasms / radiotherapy
  • Brain Neoplasms / surgery
  • Catheterization / instrumentation
  • Catheterization / methods
  • Equipment Safety*
  • Humans
  • Iodine Radioisotopes / chemistry*
  • Iodine Radioisotopes / therapeutic use
  • Iodine Radioisotopes / urine
  • Occupational Health*
  • Radiotherapy Dosage
  • Solutions / chemistry
  • Solutions / therapeutic use
  • Time Factors

Substances

  • Benzenesulfonates
  • Iodine Radioisotopes
  • Solutions
  • iotrex