Tapering off long-term benzodiazepine use with or without group cognitive-behavioural therapy: three-condition, randomised controlled trial

Br J Psychiatry. 2003 Jun:182:498-504. doi: 10.1192/bjp.182.6.498.

Abstract

Background: Benzodiazepine withdrawal programmes have never been experimentally compared with a nonintervention control condition.

Aims: To evaluate the efficacy and feasibility of tapering off long-term benzodiazepine use in general practice, and to evaluate the value of additional group cognitive-behavioural therapy (CBT).

Method: A 3-month randomised, 3-month controlled trial was conducted in which 180 people attempting to discontinue long-term benzodiazepine use were assigned to tapering off plus group CBT, tapering off alone or usual care.

Results: Tapering off led to a significantly higher proportion of successful discontinuations than usual care (62% nu. 21%). Adding group CBT did not increase the success rate (58% v. 62%). Neither successful discontinuation nor intervention type affected psychological functioning. Both tapering strategies showed good feasibilityin general practice.

Conclusions: Tapering off is a feasible and effective way of discontinuing long-term benzodiazepine use in general practice. The addition of group CBT is of limited value.

Publication types

  • Clinical Trial
  • Randomized Controlled Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged
  • Analysis of Variance
  • Anti-Anxiety Agents / administration & dosage*
  • Anti-Anxiety Agents / adverse effects
  • Attitude of Health Personnel
  • Cognitive Behavioral Therapy*
  • Combined Modality Therapy / methods
  • Diazepam / therapeutic use
  • Family Practice
  • Female
  • Humans
  • Long-Term Care
  • Male
  • Middle Aged
  • Patient Compliance
  • Patient Satisfaction
  • Psychotherapy, Group
  • Substance Withdrawal Syndrome / etiology

Substances

  • Anti-Anxiety Agents
  • Diazepam