[Progress in the study of physiological function of sphingosine 1-phosphate]

Sheng Li Ke Xue Jin Zhan. 2003 Jan;34(1):16-20.
[Article in Chinese]

Abstract

Sphingosine 1-phosphate, a bioactive sphingolipid produced from the metabolism of sphingomyelin, play important roles in diverse biological process, including cell proliferation, survival, cytoskeleton changes, migration, angiogenesis, wound healing and embryonic development. Here we review the role of sphingosine 1-phosphate in cell biological function regulation and signal transduction.

Publication types

  • English Abstract
  • Review

MeSH terms

  • Animals
  • Cells, Cultured
  • Hematopoietic System / physiology
  • Humans
  • Lysophospholipids*
  • Receptors, Cell Surface / genetics
  • Receptors, Cell Surface / physiology
  • Receptors, G-Protein-Coupled*
  • Receptors, Lysophospholipid
  • Signal Transduction
  • Sphingosine / analogs & derivatives*
  • Sphingosine / physiology*

Substances

  • Lysophospholipids
  • Receptors, Cell Surface
  • Receptors, G-Protein-Coupled
  • Receptors, Lysophospholipid
  • sphingosine 1-phosphate
  • Sphingosine