Inhibitors of the NOS enzymes: a patent review

IDrugs. 2003 Jan;6(1):57-65.

Abstract

This review covers the recent literature on inhibitors of nitric oxide synthase (NOS) between 2001 and June 2002. Some of the potential therapeutic uses of selective NOS inhibitors are highlighted in the introduction, while the main part of the review covers the patent literature of small molecule NOS inhibitors being investigated primarily by the pharmaceutical industry.

Publication types

  • Review

MeSH terms

  • Animals
  • Drug Industry
  • Enzyme Inhibitors / chemistry*
  • Enzyme Inhibitors / pharmacology
  • Humans
  • Nitric Oxide / metabolism*
  • Nitric Oxide Synthase / antagonists & inhibitors*
  • Patents as Topic

Substances

  • Enzyme Inhibitors
  • Nitric Oxide
  • Nitric Oxide Synthase