Abstract
A rapid in-house mycobacteriophage-based assay to identify multidrug resistance by detecting the rifampin susceptibility of Mycobacterium tuberculosis in a microtiter plate format was evaluated. The sensitivity, specificity, and overall accuracy of the assay were 100%. This test is rapid to perform and suitable for widespread implementation.
Publication types
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Evaluation Study
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Research Support, Non-U.S. Gov't
MeSH terms
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Antibiotics, Antitubercular / pharmacology*
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Drug Resistance, Multiple, Bacterial*
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Humans
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Microbial Sensitivity Tests / methods
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Mycobacteriophages / physiology*
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Mycobacterium tuberculosis / drug effects*
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Mycobacterium tuberculosis / virology*
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Rifampin / pharmacology*
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Time Factors
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Tuberculosis / microbiology
Substances
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Antibiotics, Antitubercular
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Rifampin