Sequence analysis of the matrix (M2) protein gene of avian pneumovirus recovered from turkey flocks in the United States

Arshud M Dar; Shirin Munir; Sagar M Goyal; Vivek Kapur

doi:10.1128/JCM.41.6.2748-2751.2003

Sequence analysis of the matrix (M2) protein gene of avian pneumovirus recovered from turkey flocks in the United States

J Clin Microbiol. 2003 Jun;41(6):2748-51. doi: 10.1128/JCM.41.6.2748-2751.2003.

Authors

Arshud M Dar¹, Shirin Munir, Sagar M Goyal, Vivek Kapur

Affiliation

¹ Biomedical Genomics Center, Department of Veterinary PathoBiology, College of Veterinary Medicine, University of Minnesota, St. Paul, Minnesota 55108, USA.

Abstract

We here report the comparative sequence and phylogenetic analysis of the avian pneumovirus subgroup C (APV C) matrix (M2) gene of cell culture-adapted isolates and clinical samples. Limited heterogeneity was observed among the M2 sequences, suggesting that diagnostic tests and vaccines against APV C are likely to exhibit broad cross-reactivity.

Publication types

Comparative Study
Research Support, Non-U.S. Gov't

MeSH terms

Amino Acid Sequence
Animals
Metapneumovirus / genetics
Metapneumovirus / isolation & purification*
Molecular Sequence Data
Paramyxoviridae Infections / veterinary*
Paramyxoviridae Infections / virology
Poultry Diseases / virology
Sequence Alignment
Sequence Analysis, DNA*
Sequence Homology, Amino Acid
Turkeys / virology*
Viral Matrix Proteins / genetics*

Substances

Viral Matrix Proteins
M2 protein, turkey rhinotracheitis pneumovirus