[Graves' ophthalmopathy: diagnosis and highlights on etiopathogenesis and treatment]

Tunis Med. 2003 Mar;81(3):149-55.
[Article in French]

Abstract

It's due to extraocular tissues enlargement: extraocular muscles. Thyroid stimulating receptor antibodies were first incriminated. However, Graves' proptosis can appear several months or years before development of goiter or thyrotoxicosis. Different treatment are possible: glucocorticoids, radiotherapy, surgical orbitary decompression, classical surgery. Treatment of hyperthyroidism has to be undertaken similarly. Classically, surgical or medical treatment with antithyroid drugs were indicated.

Publication types

  • English Abstract
  • Review

MeSH terms

  • Administration, Oral
  • Adrenal Cortex Hormones / therapeutic use
  • Anti-Inflammatory Agents / administration & dosage
  • Anti-Inflammatory Agents / therapeutic use
  • Antithyroid Agents / therapeutic use
  • Diagnosis, Differential
  • Graves Disease* / diagnosis
  • Graves Disease* / drug therapy
  • Graves Disease* / etiology
  • Graves Disease* / radiotherapy
  • Graves Disease* / surgery
  • Humans
  • Iodine Radioisotopes / therapeutic use
  • Methylprednisolone Hemisuccinate / administration & dosage
  • Methylprednisolone Hemisuccinate / therapeutic use
  • Octreotide / administration & dosage
  • Octreotide / therapeutic use
  • Prednisone / administration & dosage
  • Prednisone / therapeutic use
  • Prognosis
  • Radiotherapy Dosage
  • Time Factors
  • Vasoconstrictor Agents / administration & dosage
  • Vasoconstrictor Agents / therapeutic use
  • Visual Acuity

Substances

  • Adrenal Cortex Hormones
  • Anti-Inflammatory Agents
  • Antithyroid Agents
  • Iodine Radioisotopes
  • Vasoconstrictor Agents
  • Methylprednisolone Hemisuccinate
  • Octreotide
  • Prednisone