[Effect of continuous extradural infusion of bupivacaine on diaphragmatic function after upper abdominal surgery]

Masui. 2003 May;52(5):500-4.
[Article in Japanese]

Abstract

Background: Diaphragmatic function is impaired after abdominal surgery. We investigated the effect of continuous extradural infusion of bupivacaine on diaphragmatic function after upper abdominal surgery using respiratory inductive plethysmography (RIP).

Methods: Ten healthy patients for upper abdominal surgery were divided into two groups; the first group of patients with continuous extradural infusion of morphine (group 1) and the second group of patients with continuous extradural infusion of morphine and bupivacaine (group 2).

Results: On the first day after surgery, there was no significant difference between the visual analogue scale scores in the two groups. Abdominal contribution to tidal volume (VAB/VT) in group 1 was significantly decreased compared to that of the pre-operative value. VAB/VT in group 2 was significantly higher than that in group 1.

Conclusions: Continuous extradural infusion of bupivacaine improves diaphragmatic function after upper abdominal surgery.

Publication types

  • Clinical Trial
  • Controlled Clinical Trial
  • English Abstract

MeSH terms

  • Abdomen / surgery
  • Aged
  • Anesthesia, Epidural*
  • Anesthetics, Local* / administration & dosage
  • Bupivacaine* / administration & dosage
  • Diaphragm / physiology*
  • Female
  • Humans
  • Male
  • Middle Aged
  • Postoperative Period

Substances

  • Anesthetics, Local
  • Bupivacaine