Intracardiac left ventricular support in beating heart, multi-vessel revascularization

J Card Surg. 2003 May-Jun;18(3):240-4. doi: 10.1046/j.1540-8191.2003.02022.x.

Abstract

Background: Less invasive operation procedures without support of extracorporeal circulation are becoming increasingly important. A basic requirement for good long-term results in such cases is, however, the complete revascularization of the affected coronary vessels. The unsatisfactorily high conversion rate from bypass operations originally planned as off-pump to conventional operations with heart-lung machines, because of the failure to reach the target vessels on the rear wall of the heart through hemodynamic instability led to investigation of the efficiency of a microaxial pump (Impella elect) placed in the left ventricle.

Methods: In a prospective project 15 of 38 consecutive patients selected for coronary revascularization with beating heart had a micro pump transaortically implanted in the left ventricle to support the heart during the operation with a flow rate of 2.5 to 3.9 l/min.

Results: With 8 of 23 patients operated on without pump support, the operation had to be converted to conventional methods with a heart-lung machine. Only one patient out of the left-ventricle-supported group had to be further operated on conventionally because of a deep intramyocardial positioned left anterior descending coronary artery (LAD) (p < 0.05). The investigated laboratory parameters, especially creatine kinase (CK), CK-MB isoenzyme, and clotting showed no significant difference. There tended to be a higher blood loss recorded with the pump-supported patients.

Conclusion: In summary, it appeared that the application of a left ventricular coaxial pump with comparable results seemed to make possible complete revascularization in nearly all patients.

Publication types

  • Comparative Study

MeSH terms

  • Aged
  • Cardiopulmonary Bypass / methods
  • Coronary Artery Bypass / instrumentation*
  • Coronary Artery Bypass / methods
  • Coronary Disease / pathology
  • Coronary Disease / surgery*
  • Coronary Vessels / pathology
  • Coronary Vessels / surgery
  • Equipment Design
  • Equipment Safety
  • Female
  • Heart Function Tests
  • Heart-Assist Devices
  • Hemodynamics / physiology
  • Humans
  • Intra-Aortic Balloon Pumping*
  • Male
  • Middle Aged
  • Myocardial Revascularization / instrumentation
  • Myocardial Revascularization / methods
  • Probability
  • Prognosis
  • Prospective Studies
  • Risk Assessment
  • Severity of Illness Index
  • Treatment Outcome
  • Ventricular Dysfunction, Left / therapy*