Cerebellitis in an adult with abnormal magnetic resonance imaging findings prior to the onset of ataxia

Arch Neurol. 2003 Jun;60(6):877-80. doi: 10.1001/archneur.60.6.877.

Abstract

Background: Brain magnetic resonance imaging (MRI) findings during acute cerebellar ataxia in cases of postinfectious cerebellitis are frequently normal. This has resulted in the use of other imaging modalities, such as single-photon emission computed tomography, to aid diagnosis.

Objective: To illustrate the chronologic occurrence of cerebellar ataxia, abnormal findings on MRI, and cerebral spinal fluid pleocytosis in an adult case of postinfectious cerebellitis.

Methods: Case report.

Results: A patient with a 6-week history of occipital headaches and only mild tandem gait difficulty had abnormal MRI findings that were consistent with cerebellar inflammation. As cerebellar ataxia progressed in parallel with cerebral spinal fluid pleocytosis, MRI findings indicative of cerebellar inflammation resolved, while single-photon emission computed tomography showed cerebellar hyperperfusion. Recovery of neurologic function was accompanied by clearing of the pleocytosis and residual MRI-detected cerebellar atrophy.

Conclusion: This case demonstrates that transient abnormalities can be detected by MRI before clinical manifestations of cerebellitis appear, while hyperperfusion detected by single-photon emission computed tomography is prolonged.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Cerebellar Ataxia / cerebrospinal fluid
  • Cerebellar Ataxia / diagnostic imaging
  • Cerebellar Ataxia / pathology*
  • Cerebellar Diseases / cerebrospinal fluid
  • Cerebellar Diseases / diagnostic imaging
  • Cerebellar Diseases / pathology*
  • Cerebellum / diagnostic imaging
  • Female
  • Humans
  • Leukocyte Count
  • Leukocytosis / pathology
  • Magnetic Resonance Imaging
  • Tomography, Emission-Computed, Single-Photon