Early prediction of the sensitivity of warfarin in elderly patients by the fall in factor VIIc and protein C at the induction of treatment

Thromb Res. 2003 Mar 15;109(5-6):287-91. doi: 10.1016/s0049-3848(03)00245-7.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Administration, Oral
  • Aged
  • Aged, 80 and over
  • Aging / blood
  • Anticoagulants / adverse effects
  • Anticoagulants / pharmacology*
  • Anticoagulants / therapeutic use
  • Aryl Hydrocarbon Hydroxylases / genetics
  • Blood Coagulation / drug effects*
  • Cytochrome P-450 CYP2C9
  • Disease Susceptibility
  • Factor VII / analysis*
  • Female
  • Genotype
  • Hemorrhage / chemically induced
  • Hemorrhage / prevention & control
  • Humans
  • International Normalized Ratio
  • Male
  • Polymorphism, Genetic
  • Predictive Value of Tests
  • Protein C / analysis*
  • Warfarin / adverse effects
  • Warfarin / pharmacology*
  • Warfarin / therapeutic use

Substances

  • Anticoagulants
  • Protein C
  • Warfarin
  • Factor VII
  • CYP2C9 protein, human
  • Cytochrome P-450 CYP2C9
  • Aryl Hydrocarbon Hydroxylases