An active-site model of prostaglandin H synthase: an iron "twin-coronet" porphyrin with an aryloxyl radical overhang and its catalytic oxygenation of 1,4-diene

Angew Chem Int Ed Engl. 2003 Jun 23;42(24):2744-7. doi: 10.1002/anie.200250431.

Authors

Eiki Matsui¹, Yoshinori Naruta, Fumito Tani, Yuichi Shimazaki

Affiliation

¹ Institute for Fundamental Research of Organic Chemistry, Kyushu University, Higashi-ku, Fukuoka 812-8581, Japan.

PMID: 12820256
DOI: 10.1002/anie.200250431

No abstract available

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Alkenes / chemistry
Binding Sites
Catalysis
Electron Spin Resonance Spectroscopy
Models, Molecular*
Oxygen / chemistry*
Prostaglandin-Endoperoxide Synthases / chemistry*
Protein Conformation

Substances

Alkenes
Prostaglandin-Endoperoxide Synthases
Oxygen