De novo pulmonary capillary hemangiomatosis occurring rapidly after bilateral lung transplantation

Marc de Perrot; Thomas K Waddell; Dean Chamberlain; Michael Hutcheon; Shaf Keshavjee

doi:10.1016/s1053-2498(02)00810-0

De novo pulmonary capillary hemangiomatosis occurring rapidly after bilateral lung transplantation

J Heart Lung Transplant. 2003 Jun;22(6):698-700. doi: 10.1016/s1053-2498(02)00810-0.

Authors

Marc de Perrot¹, Thomas K Waddell, Dean Chamberlain, Michael Hutcheon, Shaf Keshavjee

Affiliation

¹ Toronto Lung Transplant Program, Toronto General Hospital, University Health Network, University of Toronto, Toronto, Ontario, Canada.

PMID: 12821168
DOI: 10.1016/s1053-2498(02)00810-0

Abstract

A 45-year-old woman experienced diffuse bilateral pulmonary capillary hemangiomatosis within 3 months after bilateral lung transplantation. The donor was a 41-year-old man with excellent lung function and without histologic or macroscopic pulmonary lesions at the time of retrieval. This case supports the theory that persistent infection or inflammation may be an inciting factor in uncontrolled angiogenesis, leading ultimately to diffuse pulmonary capillary hemangiomatosis.

Publication types

Case Reports

MeSH terms

Adult
Biopsy
Female
Forced Expiratory Volume / physiology
Hemangioma, Capillary / etiology*
Hemangioma, Capillary / microbiology
Hemangioma, Capillary / pathology
Humans
Hypertension, Pulmonary / etiology*
Hypertension, Pulmonary / microbiology
Hypertension, Pulmonary / pathology
Lung Neoplasms / etiology*
Lung Neoplasms / microbiology
Lung Neoplasms / pathology
Lung Transplantation / adverse effects*
Male
Middle Aged
Postoperative Complications / etiology*
Postoperative Complications / microbiology
Postoperative Complications / pathology
Pseudomonas Infections / complications
Pseudomonas Infections / microbiology
Pseudomonas Infections / pathology
Pseudomonas aeruginosa
Vital Capacity / physiology