Obstinate thrombosis during percutaneous coronary intervention in a case with heparin-induced thrombocytopenia with thrombosis syndrome successfully treated by argatroban anticoagulant therapy

Catheter Cardiovasc Interv. 2003 Jul;59(3):351-4. doi: 10.1002/ccd.10536.

Abstract

We describe a case of massive coronary thrombus after the coronary stenting due to heparin-induced thrombocytopenia with thrombosis syndrome (HITTS). Only argatroban was able to resolve the thrombus. This is the first case in which argatroban successfully treated massive thrombus during percutaneous coronary intervention in a patient with HITTS.

Publication types

  • Case Reports

MeSH terms

  • Angioplasty, Balloon, Coronary / adverse effects*
  • Angioplasty, Balloon, Coronary / methods
  • Anticoagulants / administration & dosage
  • Arginine / analogs & derivatives
  • Cardiac Catheterization / methods
  • Coronary Stenosis / complications
  • Coronary Stenosis / diagnostic imaging
  • Coronary Stenosis / therapy*
  • Coronary Thrombosis / complications
  • Coronary Thrombosis / diagnostic imaging
  • Coronary Thrombosis / drug therapy*
  • Follow-Up Studies
  • Heparin / adverse effects*
  • Heparin / therapeutic use
  • Humans
  • Male
  • Middle Aged
  • Myocardial Infarction / complications
  • Myocardial Infarction / diagnostic imaging
  • Myocardial Infarction / drug therapy
  • Pipecolic Acids / administration & dosage*
  • Radiography
  • Risk Assessment
  • Sulfonamides
  • Syndrome
  • Thrombocytopenia / chemically induced*
  • Thrombocytopenia / complications
  • Treatment Outcome

Substances

  • Anticoagulants
  • Pipecolic Acids
  • Sulfonamides
  • Heparin
  • Arginine
  • argatroban