[Longitudinal approaches to the problem of clinical heterogeneity of Alzheimer-type dementia]

Vestn Ross Akad Med Nauk. 1992:(8):25-31.
[Article in Russian]

Abstract

A total of 160 patients with Alzheimer-type dementias (ATD), including 84 with Alzheimer's diseases (AD) and 76 with senile dementia (SD), were examined. The initial signs of the disease were analyzed by making a retrospective assessment of informative history data. The prospective follow-up involved clinical, neuropsychological and electrophysiological (EEC mapping, evoked potentials) studies by applying the standardized assessment of results. There was shown to be a set of clinical and paraclinical parameters for the status of ATD patients, indicating a distinct-quantitative and qualitative difference between patients with AD and those with SD and supporting the heterogeneity of ATD.

Publication types

  • Comparative Study
  • English Abstract

MeSH terms

  • Aged
  • Alzheimer Disease / classification
  • Alzheimer Disease / diagnosis*
  • Brain Mapping
  • Dementia / diagnosis
  • Diagnosis, Differential
  • Electroencephalography
  • Evoked Potentials
  • Follow-Up Studies
  • Humans
  • Retrospective Studies