Changing prevalent T serotypes and emm genotypes of Streptococcus pyogenes isolates from streptococcal toxic shock-like syndrome (TSLS) patients in Japan

T Ikebe; N Murai; M Endo; R Okuno; S Murayama; K Saitoh; S Yamai; R Suzuki; J Isobe; D Tanaka; C Katsukawa; A Tamaru; A Katayama; Y Fujinaga; K Hoashi; J Ishikawa; H Watanabe; Working Group for Group A Streptococci in Japan

Changing prevalent T serotypes and emm genotypes of Streptococcus pyogenes isolates from streptococcal toxic shock-like syndrome (TSLS) patients in Japan

Epidemiol Infect. 2003 Jun;130(3):569-72.

Authors

T Ikebe¹, N Murai, M Endo, R Okuno, S Murayama, K Saitoh, S Yamai, R Suzuki, J Isobe, D Tanaka, C Katsukawa, A Tamaru, A Katayama, Y Fujinaga, K Hoashi, J Ishikawa, H Watanabe; Working Group for Group A Streptococci in Japan

Affiliation

¹ Department of Bacteriology, National Institute of Infectious Diseases, Tokyo, 162-8640, Japan.

PMID: 12825743
PMCID: PMC2869995

Abstract

We surveyed T serotypes and emm genotypes of Streptococcus pyogenes isolates from streptococcal toxic shock-like syndrome (TSLS) patients. T1 (emm1) remained dominant through 1992 to 2000, but the dominant T3 (emm3.1) strains from 1992 to 1995 disappeared during 1996-2000. Strains of several emm genotypes emerged during 1996-2000, indicating alterations in the prevalent strains causing TSLS.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Antigens, Bacterial / genetics*
Genotype
Humans
Japan / epidemiology
Prevalence
Shock, Septic / epidemiology*
Shock, Septic / microbiology
Streptococcal Infections / epidemiology*
Streptococcal Infections / microbiology
Streptococcus pyogenes / classification*
Streptococcus pyogenes / immunology

Substances

Antigens, Bacterial