Afferent loop obstruction after distal gastrectomy is rare. We present a case of a 59-year-old women who underwent distal partial gastrectomy with Billroth-II reconstruction added Braun anastomosis for cancer of the stomach. On the 10th postoperative day, she had high-grade fever and complained of abdominal pain. We diagnosed the afferent loop obstruction by computed tomography scan. Re-operation was performed to decompress the afferent loop. New Braun anastomosis was created, but because the decompression of the biliary tract was insufficient, percutaneous transhepatic biliary drainage was performed on the 52nd post-operative day. Her clinical course subsequently improved and she was discharged on the 104th postoperative day. This paper describes the details of this unusual condition, and we discuss a review of the literature.