Optical coherence tomographic and angiographic findings of a case with subretinal toxocara granuloma

Am J Ophthalmol. 2003 Jul;136(1):188-90. doi: 10.1016/s0002-9394(03)00079-5.

Abstract

Purpose: To study a case with a subretinal Toxocara granuloma.

Design: Interventional case report.

Methods: A patient with a exudative macular lesion, diagnosed as ocular toxocariasis, was examined with optical coherence tomography (OCT) and angiography before and after systemic corticosteroid and anthelminthic therapy.

Results: In OCT images, the macular granuloma initially appeared as a highly reflective mass protruding above the retinal pigment epithelium and showed dye leakage by angiography. Posttherapy, the lesion was no longer exudative, was less elevated, and was covered by the retinal pigment epithelium. There was reticular hyperfluorescence surrounded by a hypofluorescent rim in the angiograms.

Conclusions: Subretinal Toxocara granuloma may have a presentation similar to idiopathic choroidal neovascularization (CNV) and should be included in the differential diagnosis of the idiopathic CNV.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Animals
  • Antibodies, Helminth / blood
  • Antigens, Helminth / immunology
  • Coloring Agents
  • Diagnostic Techniques, Ophthalmological*
  • Diethylcarbamazine / therapeutic use
  • Drug Therapy, Combination
  • Enzyme-Linked Immunosorbent Assay
  • Eye Infections, Parasitic / diagnosis*
  • Eye Infections, Parasitic / drug therapy
  • Female
  • Filaricides / therapeutic use
  • Fluorescein Angiography / methods
  • Glucocorticoids / therapeutic use
  • Granuloma / diagnosis*
  • Granuloma / drug therapy
  • Humans
  • Indocyanine Green
  • Interferometry / methods
  • Light
  • Prednisone / therapeutic use
  • Retinal Diseases / diagnosis*
  • Retinal Diseases / drug therapy
  • Tomography / methods
  • Toxocara / immunology
  • Toxocariasis / diagnosis*
  • Toxocariasis / drug therapy

Substances

  • Antibodies, Helminth
  • Antigens, Helminth
  • Coloring Agents
  • Filaricides
  • Glucocorticoids
  • Indocyanine Green
  • Diethylcarbamazine
  • Prednisone