Amoxicillin-induced nephritis and tubulitis in a child

Urol Int. 2003;71(1):124-6. doi: 10.1159/000071111.

Abstract

The occurrence of interstitial nephritis in patients receiving antimicrobial therapy has frequently been reported in adults while it has rarely been described in children. We report the case of a patient treated with amoxicillin who presented hallucinations and serosanguineous blisters during treatment and developed renal failure a few days after discontinuation of the drug. On renal biopsy an interstitial nephritis with tubulitis was identified.

Publication types

  • Case Reports

MeSH terms

  • Acute Disease
  • Acute Kidney Injury / drug therapy
  • Acute Kidney Injury / etiology
  • Amoxicillin / adverse effects*
  • Anti-Inflammatory Agents / therapeutic use
  • Biopsy
  • Child
  • Humans
  • Kidney / pathology*
  • Male
  • Nephritis, Interstitial / chemically induced*
  • Nephritis, Interstitial / complications
  • Nephritis, Interstitial / drug therapy
  • Penicillins / adverse effects*
  • Prednisone / therapeutic use
  • Treatment Outcome

Substances

  • Anti-Inflammatory Agents
  • Penicillins
  • Amoxicillin
  • Prednisone