Capecitabine induced cutaneous hyperpigmentation: report of a case

J Drugs Dermatol. 2002 Sep;1(2):202-5.

Abstract

We report an unusual case of cutaneous and mucosal hyperpigmentation in a thirty-six year old African American woman who was receiving capecitabine chemotherapy for Stage IV breast carcinoma. Possible etiologies for the hyperpigmentation are discussed. To our knowledge, this is the first reported case of capecitabine associated cutaneous hyperpigmentation.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Antimetabolites, Antineoplastic / adverse effects*
  • Capecitabine
  • Deoxycytidine / adverse effects*
  • Deoxycytidine / analogs & derivatives*
  • Female
  • Fluorouracil / analogs & derivatives
  • Humans
  • Hyperpigmentation / chemically induced*
  • Hyperpigmentation / pathology

Substances

  • Antimetabolites, Antineoplastic
  • Deoxycytidine
  • Capecitabine
  • Fluorouracil