Abstract
Photorhabdus is an insect-pathogenic bacterium in which oral toxicity to insects is found in two distinct taxonomic groups. Using a DNA microarray and comparative genomics, we show that oral toxicity is associated with toxin complex genes tcaABC and that this locus can be mobilized or deleted within different strains.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Administration, Oral
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Animals
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Bacterial Proteins / genetics
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Bacterial Proteins / metabolism*
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Gene Expression Profiling
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Insecta / microbiology*
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Nematoda / microbiology
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Oligonucleotide Array Sequence Analysis*
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Photorhabdus / classification
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Photorhabdus / genetics
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Photorhabdus / pathogenicity*
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Virulence
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Virulence Factors / genetics
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Virulence Factors / metabolism*
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Xenorhabdus / classification
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Xenorhabdus / genetics
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Xenorhabdus / pathogenicity
Substances
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Bacterial Proteins
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Virulence Factors