Dihydrolindbladiones, three new naphthoquinone pigments from a myxomycete Lindbladia tubulina

J Nat Prod. 2003 Jul;66(7):999-1001. doi: 10.1021/np030089x.

Abstract

Three new naphthoquinone pigments, 6,7-dimethoxydihydrolindbladione (1), dihydrolindbladione (2), and 6-methoxydihydrolindbladione (3), have been isolated from a myxomycete Lindbladia tubulina, and their structures were elucidated by spectral data. Compound 3 appreciably exhibited a reversal effect of multidrug resistance. Lindbladione (4), the major pigment of this myxomycete, was also isolated from Cribraria intricata.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Drug Resistance, Multiple / drug effects
  • Japan
  • Molecular Structure
  • Myxomycetes / chemistry*
  • Naphthoquinones / chemistry
  • Naphthoquinones / isolation & purification*
  • Naphthoquinones / pharmacology
  • Pigments, Biological / chemistry
  • Pigments, Biological / isolation & purification*
  • Pigments, Biological / pharmacology
  • Spectrophotometry, Ultraviolet

Substances

  • Naphthoquinones
  • Pigments, Biological