Fused functional-anatomic images of metastatic cancer of cervix obtained by a combined gamma camera and an X-ray tube hybrid system with an illustrative case and review of the 18F-fluorodeoxyglucose literature

Gynecol Oncol. 2003 Aug;90(2):453-7. doi: 10.1016/s0090-8258(03)00227-0.

Abstract

Background: 18F-Fluorodeoxyglucose (FDG) assessments have provided clinically important information in cervical cancer. FDG studies can now be performed by both dedicated PET systems and by new-generation gamma cameras. Hybrid systems which consist of positron emission tomography (PET) or a gamma camera with X-ray for fusion of functional-anatomic data without changing the patient's position are now available.

Case: A woman with newly diagnosed cervical cancer underwent preoperative FDG studies using a hybrid gamma camera. In addition to the known primary tumor, FDG detected heretofore unidentified metastatic disease at the liver, bone, and para-aortic lymph nodes: the treatment approach was consequently altered to chemo- and radiotherapy. The fused images provided precise localization of the lesions, guiding bone biopsy and radiation field planning.

Conclusion: When PET is unavailable, a modified gamma camera can provide clinically relevant data in patients with cervical cancer.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Bone Neoplasms / diagnostic imaging
  • Bone Neoplasms / secondary*
  • Female
  • Fluorine Radioisotopes
  • Fluorodeoxyglucose F18*
  • Gamma Cameras
  • Humans
  • Liver Neoplasms / diagnostic imaging
  • Liver Neoplasms / secondary*
  • Lymph Nodes / diagnostic imaging
  • Lymph Nodes / pathology
  • Lymphatic Metastasis
  • Middle Aged
  • Radiopharmaceuticals*
  • Tomography, Emission-Computed
  • Uterine Cervical Neoplasms / diagnostic imaging*
  • Uterine Cervical Neoplasms / pathology

Substances

  • Fluorine Radioisotopes
  • Radiopharmaceuticals
  • Fluorodeoxyglucose F18