Abstract
Differentiation therapy is an area of oncology that is in its infancy. Theoretically, the concept of differentiation therapy involves turning a cancer cell "off" biologically and reverting to a more "benign" phenotype. Many agents have been studied over the past few years, with many already either in use clinically or showing future promise.
MeSH terms
-
Antineoplastic Agents / pharmacology*
-
Antineoplastic Agents / therapeutic use
-
Antineoplastic Combined Chemotherapy Protocols / therapeutic use
-
Arsenic / pharmacology
-
Arsenic / therapeutic use
-
Butyrates / pharmacology
-
Butyrates / therapeutic use
-
Cell Differentiation / drug effects*
-
Clinical Trials as Topic
-
Histone Deacetylase Inhibitors
-
Humans
-
Neoplasms / drug therapy*
-
Neoplasms / pathology
-
Phenylbutyrates / pharmacology
-
Phenylbutyrates / therapeutic use
-
Retinoids / pharmacology
-
Retinoids / therapeutic use
Substances
-
Antineoplastic Agents
-
Butyrates
-
Histone Deacetylase Inhibitors
-
Phenylbutyrates
-
Retinoids
-
Arsenic